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No specific dose adjustment suggested when tofacitinib coadministered with potent CYP2C19 inhibitors; lower tofacitinib dose if coadministered with the two moderate CYP3A4 and strong CYP2C19 inhibitors .Modafinil appears to be Harmless for prolonged durations at average (one hundred–200 mg) every day dosages, and huge-scale scientific trials conf